A patient's history is as important as their symptoms. It's what helps us decide if heart burn's a heart attack... if a head ache's a tumor. Sometimes patients will try to re-write their own histories. They'll claim they don't smoke, or forget to mention certain drugs... which in surgery can be the kiss of death. We can ignore it all we want, but our history eventually always comes back to haunt us. Some people believe that without history, our lives amount to nothing. At some point we all have to choose: do we fall back on what we know, or do we step forward to something new? It's hard not to be haunted by our past. Our history is what shapes us... what guides us. Our history resurfaces time after time after time. So we have to remember sometimes the most important history is the history we’re making today.

Time After Time is the twentieth episode of the third season and the 56th overall episode of Grey's Anatomy.

Short SummaryEdit

Meredith deals with an overbearing step-mother. Cristina finds herself caught between Burke and Marlow. Derek fights for the job of Chief. Alex continues the search for Jane Doe's identity. And Izzie's past comes looking for her.

Full SummaryEdit

Episode in detail.


  • Meredith Grey
  • Cristina Yang
  • Izzie Stevens
  • Alex Karev
  • George O'Malley
  • Miranda Bailey
  • Richard Webber
  • Addison Montgomery
  • Callie Torres
  • Mark Sloan
  • Preston Burke
  • Derek Shepherd
  • Jane Doe/Ava
  • Colin Marlow
  • Joan Waring
  • Charles Redford
  • Caroline Klein
  • Dustin Klein
  • Hematologist
  • Susan Grey
  • Frank Waring
  • Social Worker
  • Nurse Kate
  • Nurse Zibby
  • Young Woman
  • Hannah

Main CastEdit

Guest StarsEdit


Medical NotesEdit

Burke's PatientEdit

  • Diagnosis:
  • Treatment:
    • Ventricular reconstruction

Burke and Cristina operated together. Their patient became unstable.

Charles RedfordEdit

  • Diagnosis:
  • Treatment:
    • Heterotopic heart transplant

Colin performed a heterotopic (or piggyback) transplant on Charles. It went well.

Callie's PatientEdit

  • Diagnosis:
    • Abscess
  • Treatment:

Callie said she had a patient that had a gooey abscess which exploded on her.


  • Diagnosis:
    • Pregnancy
  • Treatment:
    • IV Antibiotics
    • Bed rest

They took pictures after her facial reconstruction to get an image out so they could hopefully find their Jane Doe's family. She was on bed rest until she delivered.

Javier RuggeroEdit

  • Diagnosis:
  • Treatment:

George called for Javier in the clinic.

Hannah KleinEdit

  • Diagnosis:
    • Acute myeloid leukemia
  • Doctors:
  • Treatment:
    • Bone marrow transplant

Hannah, 11, was diagnosed with AML a few months prior. She needed a bone marrow transplant and since Izzie is her biological mother, Hannah's parents sought her out as a possible donor. She agreed and the donation went through.

Meredith's PatientEdit

  • Diagnosis:
    • Perforation
  • Treatment:
    • Surgery

Meredith did a consult on a patient who had a perforation and needed surgery, but she was told she couldn't scrub in.

Mark's PatientEdit

  • Diagnosis:
  • Treatment:

Mark asked a nurse for an update on one of his patients.


Song Performer Scene
"You Know I'm No Good" Amy Winehouse
  • Cristina and Burke operate together. Their patient codes as Colin watches from the gallery.
"Burning" The Whitest Boy Alive
  • Cristina rants to Meredith about Colin and Meredith rants about Susan.
  • George checks on Callie as Izzie comes in from confession.
  • George and Callie make a coffee date.
"Dancing With Myself" Nouvelle Vague
  • The interns are eating together. George asks what's happening with Izzie.
  • Cristina tells Meredith what's happening with Colin.
  • Alex talks about Ava.
  • George asks Bailey about Izzie. Bailey says she won't tell him.
"Clean Getaway" Maria Taylor
  • George helps Izzie put her pants on.
  • Izzie tells George about Hannah and Hannah not wanting to meet her.
  • Izzie doesn't want to lose George as a friend. He leaves, but soon after comes back.
"Fontana Fontaine" Lullaby Baxter
  • George wheels Izzie toward Hannah's room. Izzie can't look, so George looks and tells her what he sees.
  • George helps Izzie stand up to see Hannah for herself.
"A Good Start" Maria Taylor
  • Ava tells Alex to get out of her room.
  • Mark brings Richard to a bar to pick up women.
  • Burke and Cristina talk about Colin leaving.
  • Derek is alone on the couch. Meredith calls, but he ignores it.
  • Susan comes to Meredith's door.

  • Mark sets Richard up with a woman, but he waffles when he sees how young she is.
  • Addison comes over and asks Richard to dance with her.
  • They dance.

Notes and TriviaEdit

Grey's Anatomy Episode 320 "Time After Time" Preview Promo

Grey's Anatomy Episode 320 "Time After Time" Preview Promo

  • This episode's title originated from the song Time After Time, originally sung by Cyndi Lauper.
  • This episode scored 21.12 million viewers.
  • Bailey tells Derek that if he has to choose between the Chief job and his loved one, he should pick his loved one because the job is nothing when he's all alone. Ironically, when her husband later makes her choose between her career and their marriage, she chooses her career.


Episode StillsEdit


Derek: You warned me she could become a problem.
Bailey: Who, Meredith?
Derek: You know when you love somebody, you think you can handle it all?
Bailey: You’ve done all right, both of you.
Derek: I came here to be chief, but Meredith complicates that.
Bailey: Huh. Well if this turns into an “either or”, you pick the person you love. End of story. Look, all of this means nothing if you’re alone.

See AlsoEdit

A complete overview of this episode's crew can be found here.

The Grey Matter blog post on this episode can be found here.