Mr. Bryce was the father of Meredith's first patient as an intern, Katie Bryce.
Mr. Bryce traveled with his wife to Seattle Grace Hospital when his daughter Katie was admitted there. He was extremely worried about her and frustrated with Dr. Shepherd when he could not find out what was wrong with her. Eventually, Meredith and Cristina figured it out and saved Katie's life.
He is married to Mrs. Bryce. Together, they have one daughter, Katie.