Grey's Anatomy Universe Wiki
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Brian Williams is the father of Rory Williams, a patient at Grey Sloan Memorial Hospital.

History[]

Cancer[]

His wife's family has a history of repeated cancer, which manifested in his daughter, Rory.

Rory’s Cancer[]

Rory had brain cancer at age ten which was fully cured. However, when Rory was sixteen, she was diagnosed with osteosarcoma and was also discovered to have a tumor in her chest.

Li-Fraumeni[]

Rory having three cancers by age sixteen and the family history of prominent cancer diagnoses prompted Miranda Bailey to look for a genetic reason. She discovered a mutation of the P53 gene and concluded that the family carried Li-Fraumeni Syndrome, which affects their bodies' ability to regulate cell growth.

Rory’s Death[]

Rory became unresponsive and wasn't breathing properly, so she was rushed into surgery. Despite the doctors' best efforts, Rory bled out into her chest and died. When the doctors came to tell the Williams family, they were distraught and it prompted Ariel to ask the doctors if she also had Li-Fraumeni, which she did.

Relationships[]

Romantic[]

Patricia Williams[]

Brian is married to Patricia Williams, with whom he has two daughters, Rory and Ariel.

Notes and Trivia[]

  • Brian "Smash" Williams was the name of the character played by Gaius Charles (Dr. Shane Ross) on Friday Night Lights, but that character was a football player.
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