Anatomy Jane is a doll with 24 detachable organs and extra parts to simulate pregnancy.
Meredith received an Anatomy Jane doll from her mother at the age of 5. Years later, when moving her mother's boxes, Meredith rediscovered Jane and for a whole day, she brought her around the hospital (just like she did when she was 5). She used the doll to help explain Tori Begler's tumor to her. Miranda Bailey also likes Anatomy Jane.
Meredith's daughter, Zola Grey Shepherd, has her own Anatomy Jane doll, an updated version.